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A prospective trial designed to study the effectiveness of endoluminal, endoscopic gastric bypass sleeve implants in morbidly obese individuals concluded that almost half of the participants experienced a mean percentage excess weight loss (EWL) of 54% after 12 months and sustained a mean %EWL of 30% at the 14-month post-explant follow-up, while the remaining required explantation or experienced partial cuff detachment before completing 1 year

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Du G, Healy LB, David L et al (2024) ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

Patients should discuss both options with their healthcare provider to determine the most appropriate and sustainable pathway

Joanie Knight from Angie, Louisiana, and Emily Wright , a teacher in Toronto, told CNN that they have been diagnosed with severe gastroparesis, otherwise known as stomach paralysiswhich their doctors believe was either caused or exacerbated by their use of Ozempic