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SGRQ Outcomes: Mean Change in Total and Component Scores from Baseline Pooled GOLDEN-3 and -4 In GOLDEN-3 and -4, statistically significant improvements in SGRQ Total score were observed in patients receiving glycopyrrolate/eFlow CS (Figure 3a)

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These studies together (n=866 in GEM 1 and 2 and 1293 in GOLDEN-3 and -4) show that treatment with glycopyrrolate may lead to significant improvements in patients' HRQoL