Exposure to cadmium (Cd) and excess molybdenum (Mo) disrupts ovarian micronutrient balance, shifts the Th1/Th2 immune balance toward Th1, and activates ER stress, triggering ovarian necroptosis through the RIPK1/RIPK3/MLKL pathway, ultimately impairing ovarian function ( In conclusion, external factors such as environmental pollutants, immune system damage, and stress-induced OS can trigger necroptosis
as well as local blood flow and genetic modifiers
Still, we are not able to predict how drug interactions would influence the regenerative outcome, regarding the scare literature dealing with such topics
Reduced Inflammation : Studies indicate that fasting can lower inflammation levels, which is linked to various chronic diseases
Int J Mol Sci 23(20):12242