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The administered concentration of PCPA was set at 300 mg/kg via i.p

Other warnings involve severe gastrointestinal adverse reactions, delayed gastric emptying, pancreatitis, gallbladder problems, acute kidney injury related to dehydration, increased heart rate, hypoglycemia when used with certain diabetes medications, and suicidal behavior or thinking

The long-term picture in people is essentially unknown

Most importantly, persistent joint pain might dissuade patients from adhering to their prescribed medication regimen, thus negatively affecting their ability to manage their diabetes