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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Demarco B., Grayczyk J.P., Bjanes E., Le Roy D., Tonnus W., Assenmacher C.-A., Radaelli E., Fettrelet T., Mack V., Linkermann A., et al

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If nausea is severe or persistent, temporary dose reduction or slower dose titration may be necessary

Additionally, they both stimulate insulin secretion, which can have side effects or adverse effects but insulin secretion is also key to their effectiveness in lowering blood sugar