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Although they are often mentioned in the same breath, they are distinct molecules with different mechanisms and different clinical track records

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Reductive carboxylation A process that occurs in some normal and cancer cells whereby -ketoglutarate proceeds 'backwards' through the tricarboxylic acid cycle, being reduced through the consumption of NADPH by isocitrate dehydrogenase in the non-canonical reverse reaction to form citrate

Cardio: Strategic, Not Excessive Steady-state cardio burns calories and improves cardiovascular health, but doesnt combat metabolic adaptation as effectively as resistance training