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To differentiate naive CD4 + T cells into pathogenic (p) T H 17 cells, rmIL-1 (50 ng/mL) was included in the cytokine cocktail

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Pernicious anaemia , an autoimmune condition affecting approximately 2% of the UK population over 60 (and about 0.10.2% overall), destroys gastric parietal cells, eliminating intrinsic factor production and severely impairing B12 absorption