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Description

However, such non-synonymous SNP either changes the activity or its affinity with the substrate 18,19 and considered to be a risk factor for the breast 15 , head and neck 16 and hepatocellular carcinoma 20

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2 The main sources of cellular ROS are mitochondria and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, and peroxisomes containing xanthine oxidase and the inducible form of nitric oxide synthase, which produce superoxide anion and nitric oxide, respectively

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