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3.2 STING STING and autophagy are connected on four levels: (i) STING facilitates non-canonical induction of autophagy, (ii) microautophagy and selective macroautophagy can induce STING degradation, (iii) ULK1 negatively regulates STING-IRF3 signaling by phosphorylating STING, and (iv) non-canonical RAB22-mediated autophagy can promote intercellular spreading of activated STING ( Figure 4 )

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Curr Allergy Asthma Rep 14:111 Ahn YM, Shin S, Jang J-H, Jung J (2023) Bojungikgi-tang improves skin barrier function and immune response in atopic dermatitis mice fed a low aryl hydrocarbon receptor ligand diet

This substantial hepatic storage, unusual for a water-soluble vitamin, provides a buffer against deficiency