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The increase of ubiquitin and Uch-L1 was observed at the early stage of re-perfusion, after the 15 min spinal cord ischemia, and had resolved by 6 h after re-perfusion in experimental animal models

This is why amber-colored vials and dark storage are particularly important for tryptophan-containing peptides

doi: 10.1016/j.ijpharm.2011.03.014

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Cerebrolysin improves Blood-Brain-Barrier (BBB) Integrity Thrombolysis using intravenous recombinant-tissue plasminogen activator (IV tPA) is the current gold standard for the treatment of acute ischemic stroke (AIS)