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Neurosci Bull 41(4): 676690

A phase III, randomized, double-blind, placebo-controlled trial, which was open-label for the comparator liraglutide group, evaluated dulaglutide monotherapy (0.75 mg) versus placebo versus once-daily liraglutide in individuals with T2DM

This is a positive developmentit means your body is becoming healthierbut it requires careful coordination

The bio-availability of the DPP-4 inhibitors is very good and the pharmacodynamic- as well as the pharmacokinetic characteristics lead to the above mentioned clinically sufficient DPP-4 inhibition with once daily dosing (only vildagliptin has to be dosed twice daily) (18, 19)

Managing injection site reactions Redness, swelling, or itching at the injection site affects a subset of patients