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The compound exhibits the molecular formula C165H269N47O46 with a molecular weight of 3647.15 g/mol and consists of 29 amino acids representing a modified version of the first 29 amino acids of endogenous GHRH

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Because FOXO4-DRIs mechanism depends on disrupting the FOXO4p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population leaving FOXO4-low non-senescent cells largely unaffected

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