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Following discovery of a sparse number of occurrences of progressive multifocal leukoencephalopathy (PML) in those taking a FAE, median duration of FAE therapy to PML symptom onset or appearance of first PML brain lesion was 31 months (range 6110), with median duration of lymphocytopenia to PML symptoms being 23 months (range 672)

Global gene profiling of aging lungs in Atp8b1 mutant mice

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Immunofluorescence staining was performed to assess macrophage polarization, with CD86 serving as a marker for pro-inflammatory M1 macrophages and CD206 for anti-inflammatory M2 macrophages