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However, avoid excessive doses potentially interfering with necessary acute inflammation

The ADA recommends GLP-1 RAs as a first line in ASCVD or high risk for ASCVD with or without metformin [7] and lifestyle management in T2DM patients, including those with or without a high risk of CVDs and those looking to reduce the risk of hypoglycemia or promote weight loss

A growing proportion of US consumers say they use or would use GLP-1-based drugs, citing weight loss as the top reason and then diabetes

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This effect directly opposes Wegovy's appetite-suppressing mechanism, potentially reducing the medication's effectiveness in promoting weight loss