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Future directions include precision-guided treatment strategies, proactive fertility monitoring, and AI-driven decision support, with multi-omics biomarkers representing the molecular foundation for transforming reproductive medicine from reactive infertility treatment to proactive fertility management

of these, most of the candidates target metabolic disorders, such as Type 2 diabetes and obesity

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IRAK4 inhibitor mitigates joint inflammation by rebalancing metabolism malfunction in RA macrophages and fibroblasts