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PRODUCT FOCUS: PEPTIDES AND PROTEINS PROCESS FOCUS: FORMULATION/STABILITY WHO SHOULD READ: ANALYTICAL AND FORMULATION DEVELOPMENT, PROCESS DEVELOPMENT, QA/QC AND REGULATORY AFFAIRS KEYWORDS: FORCED DEGRADATION, PROTEIN DEGRADATION, OXIDATION, DISULFIDE SCRAMBLING, DEAMIDATION, AGGREGATION, HYDROLYSIS LEVEL: INTERMEDIATE Advances in analytical chemistry have identified many degradation pathways that can occur in recombinant protein therapeutics over time

Cobalex is out of the animal's system within 4-6 weeks and the All Trace is released slowly over an 8 month period

(1,2) Glutathione catalyzes glutathione S-transferases (GST) and glutathione peroxidases (GPx)

The symptoms that follow are easy to misattribute