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These compounds have been extensively studied due to their many health promoting benefits, and particularly in cancer situations they appear quite powerful due to various mechanisms of action and their influence on both healthy and dodgy cells

These included amyotrophic lateral sclerosis (ALS), pulmonary fibrosis (PF), acute respiratory distress syndrome (ARDS), Duchenne muscular dystrophy (DMD), cystic fibrosis (CF), Huntingtons disease (HD), pulmonary hypertension (PH), cytokine release syndrome (CRS), frontotemporal dementia (FTD), and graft-versus-host disease (GVHD)., All selected diseases were confirmed to be classified as rare diseases by Orphanet ( a widely used global database for rare diseases

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Niacinamide is well-tolerated and it promotes skin hydration and barrier function, making it suitable for various skin types