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Future studies need to move beyond the linear explanatory framework based on a single metabolite or a single enzyme and systematically clarify, from the perspectives of temporal resolution and tissue niche resolution, the cooperative relationships between different amino acid metabolic axes and the TCA cycle, OXPHOS, and other immunometabolic modules (139)

Pharmas potential breakthroughs in AI, ADCs, and GLP-1 receptor agonists raise a critical question: can innovation outpace the relentless rise of chronic disease

Even when patients take levothyroxine or other thyroid replacement medications, metabolic rate may remain slower than in people without thyroid disease

The relationship between progressive multifocal leukoencephalopathy and GSH still remains unknown

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