I recall as a student, almost 30 years ago, contending with chronic laminitis cases in the university hospital and on farm calls
GHK-Cu activates TGF-beta superfamily signaling and bone morphogenetic protein (BMP) pathways, promoting tissue remodeling and repair

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central ER signaling might be modulating the actions of GLP-1 on food-reward behavior (Richard et al., 2016)