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The exclusion criteria involve conditions or lifestyle behaviors that result in abnormalities of liver function tests, which can be independently responsible for depleted glutathione levels or inflammation

Clinical trials thus far have produced impressive results- for example the Step 5 trial measured an average decrease in body weight over a 2 year period of 15.2% for patients using semaglutide, versus 2.6% with placebo

Finally, due to the lack of evidence of efficacy, metformin, acarbose, dipeptidyl peptidase IV inhibitors, and insulin are not recommended for the treatment of NAFLD [33]

Patients should verify current benefits directly with their plan and discuss covered alternatives with their clinician

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