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Serious side effects include pancreatitis (severe abdominal pain), gallbladder disease, acute kidney injury, thyroid tumors (boxed warning), and diabetic retinopathy complications

Although the efficacy of GHK-Cu has been recognized, there are certain limitations in its application, such as higher cost, thicker skin feel, and intolerance to high temperatures

Cardiovasc Diabetol (2005) 4:5

Sticking to, or even identifying, a single portion is another potential roadblock

And your brain interprets those signals as that uncomfortable, pressurized fullness that makes you want to unbutton your pants after eating what used to be a normal-sized meal