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This receptor-level distinction is what mechanistically separates the two, despite both falling under the broader category of growth hormone secretagogue research

Significance was determined using MantelCox test

The mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving blood flow, and modulation of dopamine and serotonin systems

They are also not approved by the FDA (Food and Drug Administration) for muscle enhancement

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