Emideltide or DSIP was not identified by name in the 2026 World Anti-Doping Agency Prohibited List reviewed for this article
Blood collected prior to the morning feeding on day 0, 28, and 56 was analyzed for hydrogen peroxide (H 2 O 2 ) production and concentration, superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) activities, concentrations of malondialdehyde (MDA), cytokines [interleukin (IL)-4, IL -6, IL -8, IL -10 and tumor necrosis factor ], and caffeine, and mRNA expression of IL -1 , Nrf2 , and HMOX1

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[PubMed ID: 28074664]
The sublingual route may be simpler to prepare and administer than nasal spray but has its own challenges, including peptide degradation by salivary enzymes and the difficulty of keeping the solution under the tongue long enough for absorption