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The combination of three genes, CDO1 (cysteine dioxygenase type 1), HOXA9 (homeobox A9), and TAC1 (tachykinin, precursor 1) has shown great promise in both the early diagnosis and staging of NSCLC (Wrangle et al., 2014)
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These genes include SLC22A5 , which encodes OCTN2, IRGM and UCP2 ( 2 S, and this downregulation was associated with a higher disease severity ( 2.4 Recruitment of immune cells Within the gastrointestinal (GI) tract, the innate immune system comprises epithelial cells, neutrophils, macrophages, dendritic cells, and natural killer (NK) cells ( 2.5 Impaired antioxidant defense system Antioxidants play a major role in mitigating ROSs effects to maintain the bodys redox balance
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