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In muscle tissue, IGF-1 LR3 is instrumental in increasing the DNA and RNA synthesis, which are crucial for protein synthesis and muscle cell proliferation, leading to hyperplasia (increase in the number of muscle cells) and hypertrophy (enlargement of existing muscle cells)

To dissect a possible dependency of cholesterol on desmosterol to suppress ferroptosis, we used AY9944 to inhibit DHCR7

5-LOXs play a significant role in the intestines by catalyzing the oxidation of arachidonic acid

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