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Islet-reactive CD8(+) T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

This contrasts with the effects of phenylephrine, which produces a pressor response accompanied by a baroreceptor mediated bradycardia, and often an associated decrease in cardiac output

In prostate cancer cells, SMALL REGULATORY RNA INVOLVED IN GSTP1 EXPRESSION MicroRNAs (miRNAs) constitute a large family of regulatory non-coding (nc)RNAs ( Accumulating evidence suggest that, as most mRNAs, the level of GSTP1 transcripts can potentially be regulated by several miRNAs

Changes in the oxidative stress appear in an early stage of the disease and continue for a longer period of time than the clinical expression

Despite substantial progress, UPS-based therapies face key obstacles, including achieving substrate specificity and efficient CNS delivery