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The compound was discovered in 1973 by Loren Pickart, who noticed that blood plasma from young people could make liver cells from older people behave like younger tissue

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[1] [4] Metformin first-line therapy for type 2 diabetes, though it more commonly causes diarrhoea rather than constipation

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While a bit rare, Semaglutide has shown some more severe side effects during testing, including: Allergic reactions (including swelling of the face, tongue, or throat