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Chronic neuroinflammation is believed to contribute significantly to Parkinsons disease progression, and GLP-1 therapies may help suppress inflammatory signaling pathways

Oral formulations are being explored for stability and systemic effects related to gut integrity and overall wellness

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GLP-1 also acts on the cardiovascular system, either directly binding to GLP-1R in cardiomyocytes and vascular smooth muscle cells, and indirectly, by its CNS actions (Baggio et al., 2017

Finally, the combination of GLP-1 RAs with anti-inflammatory or antithrombotic medications can be a promising field to improve prevention and management of coronary events