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However, chronic insomnia can sometimes be caused by underlying medical issues such as anxiety disorders, hormone imbalances, sleep apnea, or medication side effects

The HMRD in PASC pathology is a cumulative clinical outcome of several causative mechanisms comprising both SARS-CoV-2-derived virulence factors, as well as a multitude of host cellular factors and innate responses

ALA further enhances this process by improving intracellular glucose oxidation

Thus, in the presence of both GSH and H 2 O 2 , Mn 3 O 4 preferentially catalyzes the reaction between GSH and H 2 O 2 rather than solely reacting with GSH

10.1096/fj.202100067R FASEB J