The Lyo-Ready Genotyping Direct qPCR Blood mix is engineered for highly specific allelic discrimination, even in the presence of inhibitors found in blood, serum or plasma
Mechanism of Action Enzymatic Protection Mechanism : The phenylacetyl group acts as a protective shield that redirects glutathione-degrading enzymes away from the core glutathione molecule, forcing these enzymes to cleave the phenylacetyl group instead and releasing active glutathione intracellularly
J Genet Eng Biotechnol 2021
Alimentary Pharmacology and Therapeutics,27, 104119
However, clinical implementation still faces challenges, as the median turnaround time varies across different cancer types, which also depends on the source of samples and the type and scope of drug screening [75, 148, 151, 157, 174]