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Biofilm-resident bacteria exhibit a reduced metabolism and an altered proteome compared to their planktonic counterparts, features that contribute to their reduced susceptibility to immune effectors and commonly used antibiotic treatments (Novotny et al., 2019)
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Nevertheless, more data are warranted ( Managing surgery while using biologics Surgery is an integral component for the management of HS and can alleviate pain and symptoms associated with HS ( Summary and conclusions This narrative review aims to serve as a management guide for GPs, with a particular focus on biologic treatment, with the hope to bridge the gap between primary care and specialist dermatology care for HS
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