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Additionally, they are termed immunoregulatory cells for their ability to produce cytokines/chemokines that shape B/T cell responses and influence DC/macrophage/neutrophil functions, reflecting the complex biological network underlying their functions and supporting their value in immunotherapy (113, 114)

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For example, anti-inflammatory drug stored in pH-sensitive nanoparticles that can only break and release their carrying antioxidant in the microenvironment of tumours, which are known to be lower in pH than normal tissues in many cancers [301]

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When in doubt, erring on the side of caution makes sense

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In obesity, IL-6 induces an inflammatory response in white adipose tissue (WAT) [35]

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