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Despite the widespread use of synthetic pharmaceuticals (Tamatam and Mohammed, 2024), these natural bioactives have long been valued in traditional medicine and are increasingly recognized for their multi-targeted biological mechanisms and generally favorable safety profiles (Hoenders et al., 2024

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In addition, NTS neurons projecting to multiple forebrain regions contribute to both physiological and emotional regulation (50)

Staying at home and handling things independently allows people to avoid the social stigma and scrutiny that sometimes comes with reaching out for help overcoming addiction