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Vitamin B12 should be supplemented in vegetarians who do not get adequate amounts of B12 from diet or patients consuming a low calorie/low protein diet

5.2 Pancreatitis In glycemic control trials, acute pancreatitis was confirmed by adjudication in 7 OZEMPIC-treated patients (0.3 cases per 100 patient years) versus 3 in comparator-treated patients (0.2 cases per 100 patient years)

A placebo-controlled study of 72 patients with type 2 diabetes found that oral administration of lipoic acid at doses of 600 mg/day, 1,200 mg/day or 1,800 mg/day improved insulin sensitivity by 25% after four weeks of treatment (58)

This method is often used to treat or prevent vitamin B12 deficiency, which can lead to serious health problems if left untreated