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This system mediates a 1:1 exchange of extracellular cystine for intracellular glutamate, enabling cystine uptake and subsequent conversion into L-cysteine, which is used for the synthesis of GSH ( Erastin and RAS-selective lethal small molecule 3 (RSL3) are well-established ferroptosis inducers ( Transcription factors regulate SLC7A11 expression and thus modulate ferroptosis

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Eat small portions : Stop eating before feeling full to minimize nausea

Several independent studies have also shown that treatment with arimoclomol, a co-inducer of heat shock proteins, is protective against toxic mutant SOD1 aggregates, delays disease progression and improves motor function in SOD1 G93A mice (Kieran et al., 2004

Your healthcare team can provide personalised advice whilst ensuring your diabetes remains well-controlled