Data for both agonisers, semaglutide and tirzepatide , start to show trends towards increase in body weight over time (peak reduction around 40-50 weeks since treatment initiation)
Muscle preservation during GLP-1 or medical weight-loss treatment depends heavily on protein intake, resistance training, adequate nutrition, dose management, sleep, hormones, and medical monitoring
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Semaglutide, tirzepatide, and high dose dulaglutide have been deemed to have very high likelihood of achieving adequate blood sugar control, while other GLP-1s have been deemed highly likely