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During the early escalation phase, when doses are 1 to 4mg weekly, many researchers notice that effects feel strongest in the first 3 to 4 days after injection and diminish toward the end of the week

For example, hydroxamic acid mixtures such as Fimepinostat and Tinostamustine have shown promising antitumor effects (123)

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These ROS possess strong oxidizing power and high reactivity, thereby inducing rapid lipid peroxidation in bacteria (Pereira et al., 2013