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doi: 10.1074/jbc.272.33.20313

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The developed models were used to investigate the initial dose for pediatric patients (2 of 30), the potential for DDIs caused by delayed gastric emptying (2 of 30), and the pharmacokinetics of once-monthly dosing (1 of 30) (Table 6)

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Ultimately, we anticipate that the continued development of precise and effective senotherapeutic interventions will lead to the targeted elimination of senescent cells, their detrimental SASP, and improved health outcomes in age-related diseases such as AD