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Indeed, at the end of the study, the decrease in SMI exceeded 40% of total weight loss in only 18% of patients and, most importantly, the HG and MQI (both indicative of muscular functional status) were not significantly different at each time compared to baseline (see Table 4)

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This lipid radical reacts with molecular oxygen to form a lipid peroxyl radical (LOO), which can propagate the chain reaction by abstracting hydrogen atoms from neighboring lipids, leading to the generation of more lipid radicals and peroxyl radicals [9]

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In this small trial, 71 patients with biopsyproven compensated cirrhosis and BMI 27 kg/m 2 (75% with T2D, mean BMI 34.9 kg/m 2 ) were randomised to semaglutide 2.4 mg once weekly ( n = 47) or placebo ( n = 24) for 48 weeks

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