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It is worth mentioning however, that multiple regression analysis highlighted that the Val66Met polymorphism may affect serum levels of BDNF through a complex interaction with gender and in response to specific treatments such as IFN- 48,57 or linked to neurophysiologic response associated with working memory processes 58

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COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was believed to interact with Hb, facilitating the removal of heme, which was proposed by Liu and Li as likely pathway for the loss of function of hemoglobin (Hb) and the accumulation of free heme resulting in elevated OS

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