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That same year, Cigna completed its $67 billion acquisition of Express Scripts, pairing the second-largest U.S

Clinical evidence such as the SELECT outcomes trial, which delivered a 20% reduction in major cardiovascular events among obese adults without diabetes, underpins these policy shifts

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In parallel, excessive QA-driven NMDAR activation impairs sarco/endoplasmic reticulum Ca-ATPase function, disrupting calcium homeostasis and intracellular signalling [148]