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One of the challenges with B12 intake is that B12 is not that easily found in food very few foods are B12 rich and these are essentially meat and eggs

Ann.Nutr.Metab 2008;53(2):91-95

Common adverse effects include nausea, vomiting, diarrhoea, and constipation, which are usually transient and improve with dose titration

Common Signs and Symptoms Lack of strength in muscles Persistent weariness and fatigue Low levels of sugar in the blood Heart or liver complications in extreme cases The signs and symptoms of carnitine deficiency depend on the gravity of the case and the underlying reason

Structure of R152H GPX4 is modeled based on PDB structure 6HN3