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What the research shows: In the landmark STEP clinical trials, patients taking semaglutide lost an average of 15% of their body weight over 68 weeks
Lee SJ, Sanchez-Watts G, Krieger JP, Pignalosa A, Norell PN, Cortella A, et al
In vitro receptor agonism at Y1-R, Y2-R, and GLP-1R H188 virally transduced HEK293 cells stably expressing human GLP-1R were obtained from Novo Nordisk A/S for use in FRET assays
If you are pregnant or planning to become pregnant, discuss the potential risks and benefits of GLP-1 analogues with your healthcare provider
The ethical debates over the off-label prescribing of GLP-1 drugs have largely focused on concerns about unequal access and the potential diversion of these medications from diabetic patients who may need them most, especially during supply shortages
