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It actually causes your muscles to hold more water, which stresses muscle cells out enough to force them into further growth that training cant achieve on its own.31 An added benefit to that extra intracellular muscle volume is that youll likely see a swelling in your muscles thats greater than resistance training would provide without creatine, adding visible size to your muscles and potentially giving you a little motivational boost that your program is working

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The logic of this cascade is elegant in its simplicity and compelling in its clinical implications

creatinine clearance

This makes mental math simple and reduces measurement errors at lower doses like 1mg or 2mg