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Again, other research reports indicate that AST-120 reduced proteinuria, signs of uremia, and prolonged time to dialysis (121, 123)
More reliable detection reagents would facilitate both the basic study of this axis as well as clinical development--advances in antibody and peptide generation (such as those employed by the Institute for Protein Innovation) will hopefully be leveraged to improve sensitivity and specificity of clinical assays
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Another potential limitation is the uncertainty surrounding the nature of molecular damage (including that which accumulates with aging) and its effects on enzyme function, which we modeled as perturbations to individual kinetic parameters
Step-by-step mixing process Now for the actual process
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