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Accordingly, selective targeting of GSH-dependent nodes (such as cysteine transport, mitochondrial GSH import, compartmentalized GSH degradation, or NADPH-dependent regeneration) may offer greater specificity and efficacy than indiscriminate redox perturbation

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Gottlieb & Punjabi report that sleep apnea "is associated with a 2- to 3-fold increased risk of cardiovascular and metabolic disease." However, it is not clear how many of these severe complications remain after controlling for obesity and lack of exercise

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