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Certain health conditions, medications, and life circumstances add layers of complexity that make cycling between semaglutide and tirzepatide either more risky or potentially more necessary

10.1021/jacs.6b11438

The real question, and the one that matters most to compounders in the near term, is whether the FDA will extend enforcement discretion to these substances, allowing them to be compounded under the interim policy while the formal rulemaking process plays out