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For the last decade, pharmaceutical firms have been racing to come up with an oral small molecule alternative, with mixed success

After giving birth to her daughters in 2017 and 2023, Williams found it difficult to return to her desired weight despite intense training and healthy eating

NOT THIS ONE

Calcitriol has been shown to enhance autophagic activity in podocytes and tubular cells by restoring LC3-II expression and autophagic flux, while concurrently reducing apoptosis through the modulation of Bcl-2 and Bax expression (21)

The study is described as a first-of-its-kind global clinical trial designed to evaluate whether combining a proven multidomain lifestyle intervention with a metabolism-targeting drug, such as a GLP-1 agonist, can further reduce the risk of cognitive decline, mild cognitive impairment (MCI), and dementia in at-risk older adults