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Semaglutide improved symptoms, physical limitations, and led to greater weight loss across diuretic use categories in patients with HFpEF, says study author Kavita Sharma, MD, of Johns Hopkins University School of Medicine, in a release

Alternative approaches to treatment intensification, including a scenario where modeled patients continued GLP-1 receptor agonists alongside basal insulin before intensification to basal-bolus insulin therapy, were explored in sensitivity analyses

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This potential restoration of fertility makes reliable contraception particularly important for women not planning pregnancy

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