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Medications in this class such as semaglutide (Wegovy/Ozempic) and tirzepatide (Zepbound/Mounjaro) act by mimicking GLP-1's effects: They reduce appetite and increase feelings of fullness
A phase II trial in GHD adults (n=32) reported IGF-1 normalization in 5075% of participants at 30120 g/kg monthly, which was observed to be comparable to daily GH therapy [pubmed.ncbi.nlm.nih.gov]
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BMJ 374, n1682
More research is needed to grasp the coffee and myeloma risk link
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